HCID 20560300, compound → HCID 20560301, compound

HRID 1659319Notes

Reaction equation

HRID 1659319 reaction equation
[C:1]1([Se:7][C:8]2[CH:9]=[CH:10][C:11]([N+:15]([O-])=O)=[C:12]([CH:14]=2)[NH2:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>Cl>[NH2:15][C:11]1[CH:10]=[CH:9][C:8]([Se:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:14][C:12]=1[NH2:13]

Participants

3

Reactant 1

HCID 20560300HCID 20560300, compound

Product 1

HCID 20560301HCID 20560301, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of stannous chloride dihydrate (50 g.) in concentrated hydrochloric acid (100 ml.) was stirred and heated at 60°-70° C. while 5-phenylseleno-2-nitroaniline (14.6 g.) was added in portions. The mixture was stirred at that temperature for 2 hours, and was then cooled and filtered. The solid product was stirred with concentrated sodium hydroxide solution and extracted with ether. The ether extract was separated and dried, and the solvent was evaporated to give the required starting material, 1,2-diamino-4-phenylselenobenzene as a yellow oil which slowly crystallised.

Workup

  1. additionwas added in portions
  2. temperaturewas then cooled
  3. filtrationfiltered
  4. stirringThe solid product was stirred with concentrated sodium hydroxide solution
  5. extractionextracted with ether
  6. extractionThe ether extract
  7. customwas separated
  8. customdried
  9. customthe solvent was evaporated

Sources & evidence

ORD record
ord-b0631aa6414f4955b0a82f01923c24df
Source dataset
uspto-grants-1981_12
Patent number
US04303666

Reaction notes

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