Triethylamine → HCID 13175686, compound

HRID 1659352Notes

Reaction equation

HRID 1659352 reaction equation
[N+:1]([C:4]1[CH:5]=[N:6][N:7]2[C:16]=1[C:15]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:9][CH2:8]2)([O-:3])=[O:2].[CH2:17](N(CC)CC)C>C(O)C.CI>[N+:1]([C:4]1[CH:5]=[N:6][N:7]2[C:16]=1[C:15]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:9]([CH3:17])[CH2:8]2)([O-:3])=[O:2]

Participants

5

Reactant 2

HCID 8471TriethylamineHCID 135737774HCID 135737774, compound

Product 1

HCID 13175686HCID 13175686, compoundYield 87%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 6328Methyl iodideSolvent

Procedure

2.15 g (0.01 mole) of 1-nitro-5,6-dihydropyrazolo[1,5-c]quinazoline are dissolved in a mixture of 10 ml of ethanol and 20 ml of methyl iodide. 10 ml of triethylamine are added to the boiled mixture. The reaction mixture is boiled for 8 hours, then evaporated to dryness, the residue is dissolved in chloroform, washed with water, dried and evaporated. Thus, 2.0 g (87%) of 1-nitro-6-methyl-5,6-dihydropyrazolo[1,5-c]quinazoline are obtained. M.p.: 172°-173° C.

Workup

  1. customevaporated to dryness
  2. dissolutionthe residue is dissolved in chloroform
  3. washwashed with water
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-9cb513d02d774282a1696a22a09e5848
Source dataset
uspto-grants-1981_12
Patent number
US04303660

Reaction notes

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