Benzoylacetone → HCID 54257685, compound

HRID 1659481Notes

Reaction equation

HRID 1659481 reaction equation
[C:1]([CH2:9][C:10](=[O:12])[CH3:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>>[CH3:15][N:16]([CH:18]=[C:9]([C:10](=[O:12])[CH3:11])[C:1]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[O:8])[CH3:17]

Participants

3

Reactant 2

HCID 7166BenzoylacetoneHCID 78373Dimethylformamide dimethyl acetal

Product 1

HCID 54257685HCID 54257685, compound

Conditions

Temperature
80 °C

Procedure

A stirred mixture of benzoylacetone (16.2 g) and dimethylformamide dimethylacetal (16.2 ml) was heated on an oil bath at 80° C. for 40 minutes. Volatile materials were removed under vacuum and the residue was crystallised from ether to give 2-(dimethylaminomethylene)-1-phenyl-1,3-butanedione (mp 81°-83° C.).

Workup

  1. customVolatile materials were removed under vacuum
  2. customthe residue was crystallised from ether

Sources & evidence

ORD record
ord-42c2f34e11f74ed8b985baf7cded52b7
Source dataset
uspto-grants-1981_12
Patent number
US04304728

Reaction notes

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