Hydrochloric Acid → HCID 15578401, compound

HRID 1659486Notes

Reaction equation

HRID 1659486 reaction equation
[C:1]([C:9]12OC1[O:13][C:12]([C:16]([O:18]CC)=[O:17])=[CH:11][C:10]2=[O:21])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:22]>O1CCOCC1>[Cl:22][C:9]1[C:10](=[O:21])[CH:11]=[C:12]([C:16]([OH:18])=[O:17])[O:13][C:1]=1[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 12689097HCID 12689097, compound

Product 1

HCID 15578401HCID 15578401, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A solution of ethyl 6-benzoyl-5-oxo-2,7-dioxabicyclo[4.1.0]-hept-3-ene-3-carboxylate (2.9 g) prepared as in Example 44, in dioxan (30 ml) and concentrated hydrochloric acid (10 mol) was heated under reflux for 2 hours. The solution was evaporated under vacuum and the solid residue was crystallised from ethyl acetate-petroleum ether 60°-80° C. and then from dioxan-water to give the title product (mp 216°-218° C. with decomposition).

Workup

  1. temperatureunder reflux for 2 hours
  2. customThe solution was evaporated under vacuum
  3. customthe solid residue was crystallised from ethyl acetate-petroleum ether 60°-80° C.

Sources & evidence

ORD record
ord-a7bec24b3ddf420c8d1259d60f9a572b
Source dataset
uspto-grants-1981_12
Patent number
US04304728

Reaction notes

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