HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 4-(N-methylanilino)-2-butanone oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 4-(Methyl-phenyl-amino)-butan-2-one | HCID 11412687 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-(N-methylanilino)-2-butanone oxime | HCID 86738152 | — |
Reaction Steps
Add hydroxylamine hydrochloride (4.9 g=70 mmol) in 20 ml water to a solution of 4-(N-methylanilino)-2-butanone (12.4 g=70 mmol) and sodium carbonate (8.6 g=80 mmol) in 60 ml 50% ethanol. Stir for three days, concentrate and extract with ethyl acetate. Dry, concentrate and recrystallize from ether-hexane to obtain product having a melting point 46°-49° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04304790 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-b893b9d7dc554144ad28d81d2556d762 |
| Source note | uspto-grants-1981_12 |