反应详情

Add hydroxylamine hydrochloride (4.9 g=70 mmol) in 20 ml water to a solution of 4-(N-methylanilino)-2-butanone (12.4 g=70 mmol) and sodium carbonate (8.6 g=80 mmol) in 60 ml 50% ethanol. Stir for three days, concentrate and extract with ethyl acetate. Dry, concentrate and recrystallize from ether-hexane to obtain product having a melting point 46°-49° C.

1. concentrationconcentrate
2. extractionextract with ethyl acetate
3. customDry
4. concentrationconcentrate
5. customrecrystallize from ether-hexane
6. customto obtain product