HRID1659610

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccccc1C(F)(F)F

HCID168089

SK&F 24260

C20H22F3NO4

HCID12935376

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C1=C(C)Nc2cc(-c3ccccc3)n(-c3ccc(F)cc3)c(=O)c2C1c1ccccc1C(F)(F)F

HCID20559740

未命名化合物

PROCEDURE

实验过程

This product is obtained using the procedure of Example 1 from diethyl 1,4-dihydro-4-(2-trifluoromethylphenyl)-2,6-dimethyl-3,5-pyridine dicarboxylate and N-(4-fluorophenyl)-benzimidoyl chloride (2.5 g, 9.15%).

WORKUP

后处理

customThis product is obtained

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-81e6f90549ce4da5a69dd447ebc62fdb
来源数据集: uspto-grants-1981_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04304914
来源说明: uspto-grants-1981_12

反应 SMILES

[F:1][C:2]([F:28])([F:27])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]1[C:14]([C:15]([O:17][CH2:18][CH3:19])=[O:16])=[C:13]([CH3:20])[NH:12][C:11]([CH3:21])=[C:10]1[C:22](OCC)=[O:23].[F:29][C:30]1[CH:35]=[CH:34][C:33]([N:36]=[C:37](Cl)[C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)=[CH:32][CH:31]=1>>[CH3:20][C:13]1[NH:12][C:11]2[CH:21]=[C:37]([C:38]3[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=3)[N:36]([C:33]3[CH:34]=[CH:35][C:30]([F:29])=[CH:31][CH:32]=3)[C:22](=[O:23])[C:10]=2[CH:9]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[C:2]([F:27])([F:1])[F:28])[C:14]=1[C:15]([O:17][CH2:18][CH3:19])=[O:16]