HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dihydro-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-3,5-pyridinedicarboxylic acid diethyl ester → Ethyl 1,4,5,6-Tetrahydro-2-methyl-4-(2-trifluoromethylphenyl)-5-oxo-6-(4-fluorophenyl)-7-phenyl-1,6-naphthyridine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dihydro-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-3,5-pyridinedicarboxylic acid diethyl ester | HCID 168089 | — |
| Reactant | N-(4-fluorophenyl)-benzimidoyl chloride | HCID 12935376 | — |
| Product | Ethyl 1,4,5,6-Tetrahydro-2-methyl-4-(2-trifluoromethylphenyl)-5-oxo-6-(4-fluorophenyl)-7-phenyl-1,6-naphthyridine-3-carboxylate | HCID 20559740 | — |
Reaction Steps
This product is obtained using the procedure of Example 1 from diethyl 1,4-dihydro-4-(2-trifluoromethylphenyl)-2,6-dimethyl-3,5-pyridine dicarboxylate and N-(4-fluorophenyl)-benzimidoyl chloride (2.5 g, 9.15%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04304914 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-81e6f90549ce4da5a69dd447ebc62fdb |
| Source note | uspto-grants-1981_12 |