Methane → HCID 20558614, compound

HRID 1659858Notes

Reaction equation

HRID 1659858 reaction equation
Cl[C:2]([N:4]1[C:13]2[C:8](=[CH:9][C:10]([O:14][CH2:15][CH3:16])=[CH:11][CH:12]=2)[C:7]([CH3:17])=[CH:6][C:5]1([CH3:19])[CH3:18])=[O:3].[CH4:20].C[OH:22]>>[C:2]([N:4]1[C:13]2[C:8](=[CH:9][C:10]([O:14][CH2:15][CH3:16])=[CH:11][CH:12]=2)[C:7]([CH3:17])=[CH:6][C:5]1([CH3:19])[CH3:18])([O:22][CH3:20])=[O:3]

Participants

4

Reactant 3

HCID 297MethaneHCID 887MethanolHCID 20558605HCID 20558605, compound

Product 1

HCID 20558614HCID 20558614, compound

Procedure

1-Chlorocarbonyl-6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline (2.8 g) was dissolved with stirring in abs. methanol (10 ml). Stirring continued at room temperature for 1 hour. The solution was then treated with active charcoal, filtered and evaporated to dryness, yielding colourless, oily material which crystallized on standing. Pure 1-carbomethoxy-6-ethoxy-1,2-dihydro2,2,4-trimethylquinoline (2.2 g) was obtained by recrystallisation from methanol.

Workup

  1. stirringStirring
  2. filtrationfiltered
  3. customevaporated to dryness
  4. customyielding colourless
  5. customoily material which crystallized

Sources & evidence

ORD record
ord-a033fff7aa6a49f7966a4d2abf768b9a
Source dataset
uspto-grants-1981_12
Patent number
US04305932

Reaction notes

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