HCID 12520066, compound → 3-Isopropyl-5-(2-hydroxy-styryl)-isoxazole

HRID 1659888Notes

Reaction equation

HRID 1659888 reaction equation
[CH:1]([C:4]1[CH:8]=[C:7]([CH2:9]P(OCC)(=O)OCC)[O:6][N:5]=1)([CH3:3])[CH3:2].COC([O:22][C:23]1[CH:30]=[CH:29][CH:28]=[CH:27][C:24]=1[CH:25]=O)C>>[CH:1]([C:4]1[CH:8]=[C:7]([CH:9]=[CH:25][C:24]2[CH:27]=[CH:28][CH:29]=[CH:30][C:23]=2[OH:22])[O:6][N:5]=1)([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 12520066HCID 12520066, compoundHCID 12520069Diethyl (3-isopropyl-isoxazol-5-yl)methanephosphonate

Product 1

HCID 1360819203-Isopropyl-5-(2-hydroxy-styryl)-isoxazole

Procedure

Using the method described in Example I, 32 g (0.12 mole) of diethyl (3-isopropyl-isoxazol-5-yl)methanephosphonate and 22 g (0.12 mole) of o-(1-methoxy-ethoxy)-benzaldehyde are reacted and the product is recrystallized from toluene. 20 g (73% of theory) of colorless crystals, of melting point 129°-133° C., are obtained.

Workup

  1. customare reacted
  2. customthe product is recrystallized from toluene
  3. custom20 g (73% of theory) of colorless crystals, of melting point 129°-133° C., are obtained

Sources & evidence

ORD record
ord-e63477f61b1b4bc8bbd3a9ae184df4aa
Source dataset
uspto-grants-1981_12
Patent number
US04305951

Reaction notes

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