HCID 12520066, compound → 3-Tert.-butyl-5-(2-hydroxystyryl)-isoxazole

HRID 1659889Notes

Reaction equation

HRID 1659889 reaction equation
[C:1]([C:5]1[CH:9]=[C:8]([CH2:10]P(OCC)(=O)OCC)[O:7][N:6]=1)([CH3:4])([CH3:3])[CH3:2].COC([O:23][C:24]1[CH:31]=[CH:30][CH:29]=[CH:28][C:25]=1[CH:26]=O)C>>[C:1]([C:5]1[CH:9]=[C:8]([CH:10]=[CH:26][C:25]2[CH:28]=[CH:29][CH:30]=[CH:31][C:24]=2[OH:23])[O:7][N:6]=1)([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 12520066HCID 12520066, compoundHCID 12520070Diethyl (3-tert.-butyl-isoxazol-5-yl)methanephosphonate

Product 1

HCID 1359739813-Tert.-butyl-5-(2-hydroxystyryl)-isoxazole

Procedure

Using the method described in Example I, 35 g (0.13 mole) of diethyl (3-tert.-butyl-isoxazol-5-yl)methanephosphonate and 23 g (0.13 mole) of o-(1-methoxy-ethoxy)-benzaldehyde are reacted and the product is recrystallized from toluene. 24.8 g (78% of theory) of colorless crystals, of melting point 152°-155° C., are obtained.

Workup

  1. customare reacted
  2. customthe product is recrystallized from toluene
  3. custom24.8 g (78% of theory) of colorless crystals, of melting point 152°-155° C., are obtained

Sources & evidence

ORD record
ord-0a397829661e49778604a3bc534a9753
Source dataset
uspto-grants-1981_12
Patent number
US04305951

Reaction notes

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