反应详情

温度

190 °C

In a 500 ml, three-neck, round-bottom flask equipped with a thermometer, stirrer and a Stark and Dean trap with condenser were placed 119.4 g of methyl stearate, 41 g of 3-amino-2,2-dimethylpropanol and 3 g of potassium tert-butoxide. The mixture was heated to 190° C., and the methanol distilled off. The reaction mixture was dissolved in hot isopropanol and filtered. On cooling, the product crystallized, and after filtration and drying it melted at 44° C. IR showed an ester carbonyl. The pure product was obtained by washing with hot hexane. The pure product melted at 68°-69° C.

1. customIn a 500 ml, three-neck, round-bottom flask equipped with a thermometer, stirrer
2. customa Stark and Dean trap with condenser were placed
3. distillationthe methanol distilled off
4. dissolutionThe reaction mixture was dissolved in hot isopropanol
5. filtrationfiltered
6. temperatureOn cooling
7. customthe product crystallized
8. filtrationafter filtration
9. customdrying it melted at 44° C
10. customThe pure product was obtained
11. washby washing with hot hexane