Magnesium → HCID 20496799, compound

HRID 1660052Notes

Reaction equation

HRID 1660052 reaction equation
C([O:3][C:4]1[CH2:9][CH2:8][CH:7]([CH3:10])[C:6](=O)[CH:5]=1)C.[Mg].[CH2:13]([O:20][C:21]1[CH:22]=[C:23]([C:28]([CH3:36])([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH3:29])[CH:24]=[CH:25][C:26]=1Br)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([O:20][C:21]1[CH:22]=[C:23]([C:28]([CH3:36])([CH3:29])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH:24]=[CH:25][C:26]=1[C:6]1[CH:7]([CH3:10])[CH2:8][CH2:9][C:4](=[O:3])[CH:5]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 3

HCID 5462224MagnesiumHCID 109864633-ethoxy-6-methyl-2-cyclohexen-1-oneHCID 128821642-(Benzyloxy)-1-bromo-4-(2-methyloctan-2-YL)benzene

Product 1

HCID 20496799HCID 20496799, compound

Procedure

Similarly, 3-[2-benzyloxy-4-(1,1-dimethylheptyl)phenyl]-4-methylcyclohex-2-enone was prepared as an oil (4.12 g., 77%) using 3-ethoxy-6-methyl-2-cyclohexen-1-one (1.98 g., 12.9 mmoles), magnesium (0.61 g., 25.7 mmoles) and 12.9 mmoles (5.0 g.) of 2-(3-benzyloxy-4-bromophenyl)-2-methyloctane.

Sources & evidence

ORD record
ord-e5743023c5f845aea82d6d7f8880b556
Source dataset
uspto-grants-1981_12
Patent number
US04306097

Reaction notes

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