Hydrochloric Acid → HCID 86738161, compound

Participants

Reaction Steps

47.8 g. of aminomethane diphosphonic acid and 50 g. of sodium hydroxide are dissolved in 200 cc. of water. 19 g. Of acrylic acid dissolved in 50 cc. of water are added drop by drop thereto at a temperature between 20° C. and 40° C. while stirring vigorously. After the acrylic acid solution has been added, the reaction mixture is kept at a temperature of 90° C. for 30 minutes and is then neutralized with dilute hydrochloric acid. The neutralized solution is passed through a cation exchange agent and the resulting solution is concentrated by evaporation. After allowing the concentrated solution to stand for several days, N-(2-carboxy ethyl) amino methane diphosphonic acid is obtained in the form of crystals.

Provenance & Evidence