Hydrochloric Acid → HCID 13144515, compound

HRID 1660131Notes

Reaction equation

HRID 1660131 reaction equation
[O:1]=[C:2]1[N:6]2[CH2:7][CH:8]=[CH:9][CH:10]([C:11]([OH:13])=[O:12])[N:5]2[C:4](=[O:14])[NH:3]1.Cl.[CH3:16]O>>[O:1]=[C:2]1[N:6]2[CH2:7][CH:8]=[CH:9][CH:10]([C:11]([O:13][CH3:16])=[O:12])[N:5]2[C:4](=[O:14])[NH:3]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 12316326HCID 12316326, compound

Product 1

HCID 13144515HCID 13144515, compoundYield 74%

Procedure

In a manner analogous to that described in the first paragraph of Example 17, from 2,3,5,8-tetrahydro-1,3-dioxo-1H-1,2,4-triazolo[1,2-a]pyridazine-5-carboxylic acid and methanolic hydrogen chloride there was obtained in 74% yield methyl 2,3,5,8-tetrahydro-1,3-dioxo-1H-1,2,4-triazolo-[1,2-a]pyridazine-5-carboxylate of melting point 210°-213° C. (from methanol).

Sources & evidence

ORD record
ord-766f932e6eb349b4afc267e55fb58834
Source dataset
uspto-grants-1981_12
Patent number
US04307094

Reaction notes

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