Ammonium thiocyanate → HCID 5374306, compound

HRID 1660155Notes

Reaction equation

HRID 1660155 reaction equation
Cl.[C:2]1([CH2:7][NH2:8])[S:6][CH:5]=[CH:4][CH:3]=1.[S-:9][C:10]#[N:11].[NH4+]>BrC1C=CC=CC=1>[C:2]1([CH2:7][NH:8][C:10]([NH2:11])=[S:9])[S:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 15666Ammonium thiocyanateHCID 4585711-(Thiophen-2-yl)methanamine--hydrogen chloride (1/1)

Product 1

HCID 5374306HCID 5374306, compoundYield 33%

Reagents, catalysts & solvents 1

HCID 7961BromobenzeneSolvent

Procedure

2-thenylamine hydrochloride (13.35 grams, 0.089 moles) and ammonium thiocyanate (7.4 grams, 0.089 moles) in 20 ml bromobenzene were heated to reflux temperature for 90 minutes. The reaction mixture was cooled and the filtered solids washed three times with water. Recrystallization from chloroform and drying over phosphorous pentoxide yielded 5.0 grams (33%) of N-thenylthiourea, m.p. 99°-101° C.

Workup

  1. temperatureto reflux temperature for 90 minutes
  2. temperatureThe reaction mixture was cooled
  3. washthe filtered solids washed three times with water
  4. customRecrystallization from chloroform
  5. dry with materialdrying over phosphorous pentoxide

Sources & evidence

ORD record
ord-ce530ebba19b4350a38d1c61f9dfb9c7
Source dataset
uspto-grants-1981_12
Patent number
US04307106

Reaction notes

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