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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1660220Generated: November 2, 2026

1,3-Propanediamine → 2-(3-Aminopropylamino)pyrazine

https://huagongshe.com/reaction/1660220

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-PropanediamineHCID 428—
ReactantChloropyrazineHCID 73277—
Product2-(3-Aminopropylamino)pyrazineHCID 14397407—

Reaction Steps

Reacting 2-chloropyrazine with 1,3-diaminopropane by the procedure of Example 93 gives 2-(3-aminopropylamino)pyrazine and reacting this intermediate with methyl isothiocyanate gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04307101
Source datasetuspto-grants-1981_12
ORD IDord-a4b25f0d171244f2a8db1cc10112c92c
Source noteuspto-grants-1981_12