Phthalic Anhydride → HCID 12248790, compound

HRID 1660294Notes

Reaction equation

HRID 1660294 reaction equation
[C:1]1(=[O:11])[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[N+]([C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[NH:20][C:19]([CH3:24])=[CH:18]2)([O-])=O>C(Cl)CCl>[C:24]1([C:19]2[NH:20][C:21]3[C:17]([C:18]=2[C:4]([C:3]2[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=2[C:1]([OH:6])=[O:11])=[O:5])=[CH:16][CH:15]=[CH:23][CH:22]=3)[CH:4]=[CH:3][CH:2]=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 6811Phthalic AnhydrideHCID 2803132-Methyl-5-nitro-1H-indole

Product 1

HCID 12248790HCID 12248790, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

Proceeding in a manner similar to that described in part A of Example 10, 29.6 g (0.20 mole) of phthalic anhydride and 35.2 g (0.20 mole) of 5-nitro-2-methylindole were interacted in 100 ml of ethylene dichloride to obtain 2-[(2-methyl-5-nitro-3-indolyl)carbonyl]benzoic acid (Formula VIII: Ro =R1 =R2 =R3 =R6 =H; R5 =CH3 ; Y1 =5-NO2), a red brown solid melting at 144°-148° C. and showing a strong carbonyl absorption maximum at 1700 cm-1 in the infrared spectrum.

Sources & evidence

ORD record
ord-2559d2ffc0d8478ea948b51d8b7b8ab9
Source dataset
uspto-grants-1981_12
Patent number
US04307018

Reaction notes

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