HCID 20485093, compound → HCID 12786428, compound

Participants

Reaction Steps

Similarly, by replacing 5-(2-chloroethyl)-1,4-dimethylpyrimido-[1,6-a]indole with an equivalent amount of another compound of formula 1 described in Example 12 and using N-methyl-N-(1-methylethyl)amine, the following compounds of formula 1 are obtained, respectively; 9-ethyl-1,4,N-trimethyl-N-(1-methylethyl)pyrimido[1,6-a]indole-5-ethanamine, 8-methoxy-1,4,N-trimethyl-N-(1-methylethyl)pyrimido[1,6-a]indole-5-ethanamine,7-phenylmethoxy-1,4,N-trimethyl-N-(1-methylethyl)pyrimido-[1,6-a]indole-5-ethanamine,1,N-dimethyl-N-(1-methylethyl)-4-propylpyrimido[1,6-a]indole-5-ethanamine,3,4-diethyl-1,N-dimethyl-N-(1-methylethyl)pyrimido[1,6-a]indole-5-ethanamine,1,4-diethyl-N-methyl-N-(1-methylethyl)-3-phenylpyrimido[1,6-a]indole-5-ethanamine, and 4-butyl-1,N-dimethyl-N-(1-methylethyl)-3-phenylpyrimido[1,6-a]indole-5-ethanamine.

Provenance & Evidence