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HRID1660375

反应详情

EQUATION

反应方程式

HRID 1660375 的结构方程式

REACTANTS

反应物

2
结构：[N-]=[N+]=C(c1ccccc1)c1ccccc1
HCID61230

Diazodiphenylmethane

C13H10N2

结构：C=C1CSC2C(NC(=O)OC(C)(C)C)C(=O)N2C1C(=O)O
HCID12896773

未命名化合物

PRODUCTS

生成物

1
结构：C=C1CSC2C(NC(=O)OC(C)(C)C)C(=O)N2C1C(=O)OC(c1ccccc1)c1ccccc1
HCID12896775

未命名化合物

收率 66.2%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

2-Carboxy-7-tert.-butoxycarbonylamino-3-methylene-8-oxo-5-thia-1-aza-bicyclo[4.2.0]octane (21.3 g) is esterified with diphenyldiazomethane (11.2 g) in accordance with the procedure of Example 1. 2-Benzhydryloxycarbonyl-7-tert.-butoxycarbonylamino-3-methylene-8-oxo-5-thia-1-aza-bicyclo[4.2.0]octane (18.35 g) is obtained in the form of white crystals (m.p.=135°-7° C. after recrystallisation from ethyl acetate).