Lithium hydroxide, monohydrate → HCID 86613245, compound

HRID 1660710Notes

Reaction equation

HRID 1660710 reaction equation
C([O:8][C:9](=[O:19])[C@@H:10]1[CH2:14][CH2:13][CH2:12][N:11]1[CH2:15][CH:16]1[O:18][CH2:17]1)C1C=CC=CC=1.[Li+].[OH-].O>CO>[CH2:15]([N:11]1[CH2:12][CH2:13][CH2:14][C@H:10]1[C:9]([OH:19])=[O:8])[CH:16]1[O:18][CH2:17]1

Participants

4

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 86613244HCID 86613244, compound

Product 1

HCID 86613245HCID 86613245, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

N-Glycidyl-L-proline is prepared from compound 120 by hydrolyzing the benzyl ester with LiOH/H2O in methanol.

Sources & evidence

ORD record
ord-50e5bc200660409ab864b4c6ebcabca0
Source dataset
uspto-grants-2011_10
Patent number
US08030279B2

Reaction notes

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