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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1660767Generated: October 31, 2026

Isopropanol → HCID 25056266, compound

https://huagongshe.com/reaction/1660767

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropanolHCID 3776—
ReactantL-Tartaric acidHCID 444305—
ReactantEvogliptinHCID 25022354—
SolventAcetoneHCID 180—
SolventWater ethanolHCID 19096565—
ProductHCID 25056266HCID 25056266101.9%

Reaction Steps

55 mg of the compound obtained in Example 11 was dissolved in 0.56 mL of acetone to which a solution of 26 mg of L-tartaric acid in 0.35 mL of ethanol/water (9/1(v/v)) was then slowly added, followed by stirring for 30 min. 0.56 mL of 2-propanol was added thereto, followed by stirring for 10 min and filtration to afford 77 mg of the title compound as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030315B2
Source datasetuspto-grants-2011_10
ORD IDord-4a7e0fe50e384fd4a0b6b750e59b48db
Source noteuspto-grants-2011_10