HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 10702456, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,6-Difluoropyridine-3-carboxylic acid | HCID 10583070 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10702456 | HCID 10702456 | — |
Reaction Steps
A mixture of 2,6-difluoronicotinic acid (6.2 g), thionyl chloride (15 mL) and CH2Cl2 (100 mL) was heated to reflux for 3 h. The mixture was evaporated to dryness, CH2Cl2, was added and evaporated to dryness to afford 1.1 g of the 2,6-difluoronicotinic acid chloride. This material used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030318B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-41e9e743c4694a59950552fb57e6b8df |
| Source note | uspto-grants-2011_10 |