Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1660944Generated: October 30, 2026

(4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid → HCID 11993479, compound

https://huagongshe.com/reaction/1660944

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acidHCID 53213084—
Reactant4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)anilineHCID 59134564—
SolventDichloromethane methanolHCID 21226129—
ProductHCID 11993479HCID 11993479—

Reaction Steps

The title compound is prepared as described in Example 1 but using (4-imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid (Step 7.1) and 4-(4-ethyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenylamine (see WO 03/099771). Title compound: ES-MS: 523.0 [M+H]+; single peak at tR=3.00 min (System 1); Rf=0.12 (CH2Cl2/MeOH+1% NH3aq, 95:5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030311B2
Source datasetuspto-grants-2011_10
ORD IDord-7513db0da8ca46739a9f85c81d3462a9
Source noteuspto-grants-2011_10