HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodo-3-(trifluoromethyl)aniline → 2-(4-imidazo[4,5-b]pyridin-3-yl-phenyl)-N-(4-iodo-3-trifluoromethyl-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodo-3-(trifluoromethyl)aniline | HCID 23003624 | — |
| Reactant | (4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid | HCID 53213084 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 2-(4-imidazo[4,5-b]pyridin-3-yl-phenyl)-N-(4-iodo-3-trifluoromethyl-phenyl)-acetamide | HCID 11993576 | — |
Reaction Steps
The title compound is prepared as described in Example 1 but using (4-imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid (Step 7.1) and 4-iodo-3-trifluoromethyl-phenylamine. Title compound: ES-MS: 522.7 [M+H]+; single peak at tR=4.72 min (System 1); Rf=0.25 (CH2Cl2/MeOH, 95:5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030311B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-3ca40e8b3d5b411f805b271fba3d73eb |
| Source note | uspto-grants-2011_10 |