Hydrochloric Acid → HCID 67021597, compound

Participants

Reaction Steps

A mixture of (4-imidazo[4,5-b]pyridine-3-yl-phenyl)-oxo-acetic acid ethyl ester (123 mg, 0.417 mmol) and 1N LiOH (0.5 mL, 0.5 mmol) in THF (4 mL) is stirred at rt for 5 min. 1M HCl (500 μL) is then added and the resulting precipitate filtered off. (4-Imidazo[4,5-b]pyridine-3-yl-phenyl)-oxo-acetic acid is obtained as a grey solid. Title compound: ES-MS=268.05 [M+H]+; tR=0.8 min (System 2).

Provenance & Evidence