Ethyl 4-nitrophenylglyoxylate → HCID 20525885, compound

Participants

Reaction Steps

A mixture of (4-nitro-phenyl)-oxo-acetic acid ethyl ester (500 mg, 2.2 mmol) and 10% Pd/C (233 mg) in ethanol (2 mL) is stirred for 11 h under hydrogen. The reaction mixture is filtered through celite and concentrated. The yellow solid (4-amino-phenyl)-oxo-acetic acid ethyl ester is obtained. Title compound: tR=1.1 min (System 2).

Provenance & Evidence