HRID1661009

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID53213084

未命名化合物

结构：CN1CCN(Cc2cccc(-n3nc(C(C)(C)C)cc3N)c2)CC1

HCID67021548

未命名化合物

PRODUCTS

生成物

结构：CN1CCN(Cc2cccc(-n3nc(C(C)(C)C)cc3NC(=O)Cc3ccc(-n4cnc5cccnc54)cc3)c2)CC1

HCID67021595

未命名化合物

PROCEDURE

实验过程

The title compound is prepared as described in Example 28 but using 2-(4-Imidazo[4,5-b]pyridine-3-yl-phenyl)-acetic acid and 5-tert-butyl-2-[3-(4-methyl-piperazin-1-ylmethyl)-phenyl)-2H-pyrazol-3-ylamine. Title compound: ES-MS: 563.12 [M+H]+; tR=2.67 min (System 3).

WORKUP

后处理

customThe title compound is prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6bc682f37dad48e9a7d0d25805fb73ee
来源数据集: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08030311B2
来源说明: uspto-grants-2011_10

反应 SMILES

[N:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[N:3]([C:10]2[CH:15]=[CH:14][C:13]([CH2:16][C:17]([OH:19])=O)=[CH:12][CH:11]=2)[CH:2]=1.[C:20]([C:24]1[CH:25]=[C:26]([NH2:43])[N:27]([C:29]2[CH:34]=[CH:33][CH:32]=[C:31]([CH2:35][N:36]3[CH2:41][CH2:40][N:39]([CH3:42])[CH2:38][CH2:37]3)[CH:30]=2)[N:28]=1)([CH3:23])([CH3:22])[CH3:21]>>[C:20]([C:24]1[CH:25]=[C:26]([NH:43][C:17](=[O:19])[CH2:16][C:13]2[CH:12]=[CH:11][C:10]([N:3]3[C:4]4=[N:5][CH:6]=[CH:7][CH:8]=[C:9]4[N:1]=[CH:2]3)=[CH:15][CH:14]=2)[N:27]([C:29]2[CH:34]=[CH:33][CH:32]=[C:31]([CH2:35][N:36]3[CH2:37][CH2:38][N:39]([CH3:42])[CH2:40][CH2:41]3)[CH:30]=2)[N:28]=1)([CH3:23])([CH3:21])[CH3:22]