HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid → N-(5-tert-Butyl-2-[3-(4-methyl-piperazin-1-ylmethyl)-phenyl)-2H-pyrazol-3-yl)-2-(4-imidazo[4,5-b]pyridine-3-yl-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid | HCID 53213084 | — |
| Reactant | 5-tert-butyl-2-[3-(4-methyl-piperazin-1-ylmethyl)-phenyl)-2H-pyrazol-3-ylamine | HCID 67021548 | — |
| Product | N-(5-tert-Butyl-2-[3-(4-methyl-piperazin-1-ylmethyl)-phenyl)-2H-pyrazol-3-yl)-2-(4-imidazo[4,5-b]pyridine-3-yl-phenyl)-acetamide | HCID 67021595 | — |
Reaction Steps
The title compound is prepared as described in Example 28 but using 2-(4-Imidazo[4,5-b]pyridine-3-yl-phenyl)-acetic acid and 5-tert-butyl-2-[3-(4-methyl-piperazin-1-ylmethyl)-phenyl)-2H-pyrazol-3-ylamine. Title compound: ES-MS: 563.12 [M+H]+; tR=2.67 min (System 3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030311B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-6bc682f37dad48e9a7d0d25805fb73ee |
| Source note | uspto-grants-2011_10 |