HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)aniline → 2-(2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-N-(3-trifluoromethyl-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)aniline | HCID 7375 | — |
| Reactant | (2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)acetic acid | HCID 67021568 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-N-(3-trifluoromethyl-phenyl)-acetamide | HCID 67021562 | — |
Reaction Steps
The title compound is prepared as described in Example 7 but using (2,6-dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)acetic acid (Step 56.1) and 3-(trifluoromethyl)aniline. Title compound: ES-MS: 462.9/464.9 [M-H]−; tR=5.08 min (System 1); Rf=0.37 (CH2Cl2/(2N NH3 in MeOH), 95:5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030311B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-51e83efadc9049ecb7b39d1940a4cced |
| Source note | uspto-grants-2011_10 |