HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59864195, compound → 2-(2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-N-(4-diethylaminomethyl-3-trifluoromethyl-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59864195 | HCID 59864195 | — |
| Reactant | (2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)acetic acid | HCID 67021568 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 2-(2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-N-(4-diethylaminomethyl-3-trifluoromethyl-phenyl)-acetamide | HCID 67021318 | — |
Reaction Steps
The title compound is prepared as described in Example 7 but using (2,6-dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid (Step 56.1) and 4-diethylaminomethyl-3-trifluoromethyl-phenylamine (disclosed in WO2005/051366). Title compound: ES-MS: 549.9/551.9 [M+H]+; tR=3.93 min (System 1); Rf=0.28 (CH2Cl2/MeOH, 95:5+0.1% NH3aq).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030311B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-265c2d2fb37842db8479b67c25849f47 |
| Source note | uspto-grants-2011_10 |