HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59864195, compound → N-(4-Diethylaminomethyl-3-trifluoromethyl-phenyl)-2-(4-imidazo[4,5-b]pyridin-3-yl-2-methyl-Phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59864195 | HCID 59864195 | — |
| Reactant | (4-Imidazo[4,5-b]pyridin-3-yl-2-methyl-phenyl)-acetic acid | HCID 67021622 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | N-(4-Diethylaminomethyl-3-trifluoromethyl-phenyl)-2-(4-imidazo[4,5-b]pyridin-3-yl-2-methyl-Phenyl)-acetamide | HCID 67021612 | — |
Reaction Steps
The title compound is prepared as described in Example 7 but using (4-imidazo[4,5-b]pyridin-3-yl-2-methyl-phenyl)-acetic acid and 4-diethylaminomethyl-3-trifluoromethyl-phenylamine (disclosed in WO2005/051366). Title compound: ES-MS: 496.0 [M+H]+; tR=3.31 min (System 1); Rf=0.43 (CH2Cl2/MeOH, 95:5+0.1% NH3aq).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030311B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-527c41e1d4f7417f8f6748b3c10e2496 |
| Source note | uspto-grants-2011_10 |