反应详情

To a solution of tert-butyl 5-chloro-2,3-dihydrospiro[indene-1,3′-pyrrolidine]-1′-carboxylate (Prep9, 900 mg, 2.93 mol) in methanol (10 ml), HCl/CH3OH (10 ml, 3M in methanol) was added and stirred overnight at room temperature. The solvent was evaporated in vacuo to give the title compound (500 mg, y=82%).

1. customThe solvent was evaporated in vacuo