HCID 59233917, compound → HCID 67427879, compound

Participants

Reaction Steps

To a solution of tert-butyl 6-chloro-2,3-dihydrospiro[indene-1,3′-pyrrolidine]-1′-carboxylate (Prep42, 2.50 g, 8.14 mmol) in ether (50 ml), a 1N solution of hydrochloric acid-ether (50 ml) was added and stirred overnight. The mixture was washed by anhydrous ether. The residue was dissolved in DCM and concentrated to give the title compound (1.8 g, y=81.3%).

Provenance & Evidence