HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-(4-Fluoro-benzoyl)-piperidine-3-carboxylic acid hydrazide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N'-[1-(4-Fluoro-benzoyl)-piperidine-3-carbonyl]-hydrazinecarboxylic acid tert-butyl ester | HCID 66618470 | — |
| Product | 1-(4-Fluoro-benzoyl)-piperidine-3-carboxylic acid hydrazide hydrochloride | HCID 66618410 | 100% |
Reaction Steps
N′-[1-(4-Fluoro-benzoyl)-piperidine-3-carbonyl]-hydrazinecarboxylic acid tert-butyl ester was dissolved in 8 ml of 4N HCl (dioxane solution). The resulting reaction mixture was stirred at R.T. for 1 h and concentrated to afford 0.88 g (100%) of 1-(4-Fluoro-benzoyl)-piperidine-3-carboxylic acid hydrazide hydrochloride as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030331B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-d4442915d4de4dce9ab52b71642bf2c7 |
| Source note | uspto-grants-2011_10 |