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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661191Generated: November 1, 2026

Hydrochloric Acid → HCID 66618519, compound

https://huagongshe.com/reaction/1661191

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 42053071HCID 42053071—
SolventDichloromethaneHCID 6344—
ProductHCID 66618519HCID 6661851992%

Reaction Steps

To a cooled solution of (S)-3-(4-fluoro-phenylcarbamoyl)-piperidine-1-carboxylic acid tert-butyl ester (0.34 g, 1.05 mmol) in dichloromethane (5 mL) was added dropwise 5.2 mL of HCl 4N (dioxane solution) and the solution was stirred at R.T. for 45 min. The solvent was evaporated under reduced pressure to give the title compound as a white solid (0.252 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030331B2
Source datasetuspto-grants-2011_10
ORD IDord-fb011ea11f634b81902b6502d23183fd
Source noteuspto-grants-2011_10