2-Bromo-3-methylpyridine → [1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-(3-methyl-pyridin-2-yl)-methanone

HRID 1661220Notes

Reaction equation

HRID 1661220 reaction equation
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:12]=[C:13]([C:17]3[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:18]=3[O:24][CH3:25])[CH:14]=[CH:15][CH:16]=2)[CH:10]=1)=[O:5].Br[C:28]1[C:33]([CH3:34])=[CH:32][CH:31]=[CH:30][N:29]=1>>[F:23][C:21]1[CH:20]=[CH:19][C:18]([O:24][CH3:25])=[C:17]([C:13]2[CH:14]=[CH:15][CH:16]=[C:11]([N:9]3[CH:10]=[C:6]([C:4]([C:28]4[C:33]([CH3:34])=[CH:32][CH:31]=[CH:30][N:29]=4)=[O:5])[N:7]=[CH:8]3)[CH:12]=2)[CH:22]=1

Participants

3

Procedure

This compound was prepared by Method C using compound 12b and 2-bromo-3-methylpyridine. HRMS (ESI+): m/z=388.1471 [M+H]

Workup

  1. customThis compound was prepared by Method C

Sources & evidence

ORD record
ord-5c14dfcfe8b445e5848a8bcd8cca992b
Source dataset
uspto-grants-2011_10
Patent number
US08030339B2

Reaction notes

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