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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661220Generated: October 26, 2026

2-Bromo-3-methylpyridine → [1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-(3-methyl-pyridin-2-yl)-methanone

https://huagongshe.com/reaction/1661220

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-3-methylpyridineHCID 220832—
Reactant1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazole-4-carboxylic acid methoxy-methyl-amideHCID 86634428—
Product[1-(5'-Fluoro-2'-methoxy-biphenyl-3-yl)-1H-imidazol-4-yl]-(3-methyl-pyridin-2-yl)-methanoneHCID 16678706—

Reaction Steps

This compound was prepared by Method C using compound 12b and 2-bromo-3-methylpyridine. HRMS (ESI+): m/z=388.1471 [M+H]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030339B2
Source datasetuspto-grants-2011_10
ORD IDord-5c14dfcfe8b445e5848a8bcd8cca992b
Source noteuspto-grants-2011_10