2-Bromoanisole → {1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl}-(2-methoxy-phenyl)-methanone

HRID 1661326Notes

Reaction equation

HRID 1661326 reaction equation
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]3[C:18]([F:24])=[N:19][CH:20]=[CH:21][C:22]=3[F:23])[CH:12]=2)[CH:10]=1)=[O:5].Br[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[O:33][CH3:34]>>[F:24][C:18]1[C:17]([C:13]2[CH:12]=[C:11]([N:9]3[CH:10]=[C:6]([C:4]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=4[O:33][CH3:34])=[O:5])[N:7]=[CH:8]3)[CH:16]=[CH:15][CH:14]=2)=[C:22]([F:23])[CH:21]=[CH:20][N:19]=1

Participants

3

Procedure

This compound is prepared by method C using compound 12j and 2-bromoanisole

Workup

  1. customThis compound is prepared by method C

Sources & evidence

ORD record
ord-9554d5b45f5a41f0bbdc03fd9d79cc6c
Source dataset
uspto-grants-2011_10
Patent number
US08030339B2

Reaction notes

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