5-Methylthiazole → {1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl}-(5-methyl-thiazol-2-yl)-methanone

HRID 1661328Notes

Reaction equation

HRID 1661328 reaction equation
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]3[C:18]([F:24])=[N:19][CH:20]=[CH:21][C:22]=3[F:23])[CH:12]=2)[CH:10]=1)=[O:5].[CH3:26][C:27]1[S:31][CH:30]=[N:29][CH:28]=1>>[F:24][C:18]1[C:17]([C:13]2[CH:12]=[C:11]([N:9]3[CH:10]=[C:6]([C:4]([C:30]4[S:31][C:27]([CH3:26])=[CH:28][N:29]=4)=[O:5])[N:7]=[CH:8]3)[CH:16]=[CH:15][CH:14]=2)=[C:22]([F:23])[CH:21]=[CH:20][N:19]=1

Participants

3

Procedure

This compound is prepared by method C using compound 12j and 5-methylthiazole

Workup

  1. customThis compound is prepared by method C

Sources & evidence

ORD record
ord-528907fc1bbd40a3abf7cc5a30354f10
Source dataset
uspto-grants-2011_10
Patent number
US08030339B2

Reaction notes

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