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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661328Generated: October 29, 2026

5-Methylthiazole → {1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl}-(5-methyl-thiazol-2-yl)-methanone

https://huagongshe.com/reaction/1661328

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-MethylthiazoleHCID 137980—
Reactant1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazole-4-carboxylic acid methoxy-methyl-amideHCID 86634434—
Product{1-[3-(2,4-Difluoro-pyridin-3-yl)-phenyl]-1H-imidazol-4-yl}-(5-methyl-thiazol-2-yl)-methanoneHCID 16679500—

Reaction Steps

This compound is prepared by method C using compound 12j and 5-methylthiazole

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030339B2
Source datasetuspto-grants-2011_10
ORD IDord-528907fc1bbd40a3abf7cc5a30354f10
Source noteuspto-grants-2011_10