1-Bromo-4-fluorobenzene → HCID 16678204, compound

HRID 1661346Notes

Reaction equation

HRID 1661346 reaction equation
CON(C)[C:4]([C:6]1[N:7]=[CH:8][N:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([C:17]3[C:18]([O:25][CH3:26])=[N:19][C:20]([O:23][CH3:24])=[N:21][CH:22]=3)[CH:12]=2)[CH:10]=1)=[O:5].Br[C:29]1[CH:34]=[CH:33][C:32]([F:35])=[CH:31][CH:30]=1>>[CH3:24][O:23][C:20]1[N:19]=[C:18]([O:25][CH3:26])[C:17]([C:13]2[CH:12]=[C:11]([N:9]3[CH:10]=[C:6]([C:4]([C:29]4[CH:34]=[CH:33][C:32]([F:35])=[CH:31][CH:30]=4)=[O:5])[N:7]=[CH:8]3)[CH:16]=[CH:15][CH:14]=2)=[CH:22][N:21]=1

Participants

3

Reactant 2

HCID 99931-Bromo-4-fluorobenzeneHCID 866344351-[3-(2,4-Dimethoxy-pyrimidin-5-yl)-phenyl]-1H-imidazole-4-carboxylic acid methoxy-methyl-amide

Product 1

HCID 16678204HCID 16678204, compound

Procedure

This compound is prepared by method C using compound 12m and 1-bromo-4-fluorobenzene

Workup

  1. customThis compound is prepared by method C

Sources & evidence

ORD record
ord-058ac4d96f1c458da9989b20721167b0
Source dataset
uspto-grants-2011_10
Patent number
US08030339B2

Reaction notes

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