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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1661471Generated: October 30, 2026

(1S)-2-amino-1-phenylethan-1-ol → HCID 67429313, compound

https://huagongshe.com/reaction/1661471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S)-2-amino-1-phenylethan-1-olHCID 643217—
Reactant1-(4-fluorophenyl)-5-iodo-1H-indazoleHCID 59251128—
Reactant(alphaS,betaR)-beta-{[1-(4-Fluorophenyl)-1H-indazole-5-yl]oxy}-alpha-methylbenzeneethanamineHCID 59339817—
ProductHCID 67429313HCID 67429313—

Reaction Steps

Prepared from (1S)-1-phenyl-1-hydroxy-ethan-2-amine (294 mg, 2.15 mmol) and 1-(4-fluorophenyl)-5-iodoindazole (484 mg, 1.43 mmol) according to the protocol for 1a. Yield: 175 mg (23%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030340B2
Source datasetuspto-grants-2011_10
ORD IDord-ddc6fd400db54e59a2fc3305cd97174c
Source noteuspto-grants-2011_10