HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57545209, compound → HCID 57545154, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57545209 | HCID 57545209 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 57545154 | HCID 57545154 | 100.2% |
Reaction Steps
66.5 g (152 mmol) of 3-tert-butyldimethylsilyloxy-6-(2-chloroethoxy)-2-(4-chlorophenyl)benzofuran are dissolved in 500 ml of a 4 M hydrogen chloride solution in dioxane at RT under argon and stirred for 1.5 h. The mixture is concentrated to result in 49.2 g of a residue which is stored under argon and reacted further without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030347B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-68bae9bb9a4d484cb01bb54c2bc6509f |
| Source note | uspto-grants-2011_10 |