HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-Methyl-1H-indol-2-yl)boronic acid → 2-[5-(1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-isoindole-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-Methyl-1H-indol-2-yl)boronic acid | HCID 22733820 | — |
| Reactant | 2-((5-Bromopyridin-3-yl)methyl)isoindoline-1,3-dione | HCID 22992261 | — |
| Product | 2-[5-(1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-isoindole-1,3-dione | HCID 58215560 | — |
Reaction Steps
2-(5-Bromo-pyridin-3-ylmethyl)-isoindole-1,3-dione (Example 186b) and 1-methyl-indole-2-boronic acid are processed according to the method described in Example 100 to give 2-[5-(1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-isoindole-1,3-dione as a solid. MS (ESI) m/z 368.09 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030334B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-7487b10c4cd149e8804e827545253a1f |
| Source note | uspto-grants-2011_10 |