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HRID1661852

反应详情

EQUATION

反应方程式

HRID 1661852 的结构方程式

REACTANTS

反应物

2
结构：CCCCCCCC/C=C\CCCCCCCC(=O)O
HCID445639

Oleic acid

C18H34O2

结构：CC(C[PH](=O)O)CC(C)(C)C
HCID178460681

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCCC(CCCCCCCCC(=O)O)P(=O)(O)CC(C)CC(C)(C)C
HCID57909108

未命名化合物

收率 83%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCC(C)(C)OOC(C)(C)CC
催化剂HCID25320

Bis(2-methylbutan-2-yl) peroxide

C10H22O2

CONDITIONS

反应条件

温度
140 °C

PROCEDURE

实验过程

6.31 g (0.0354 moles) of 2,4,4-trimethylpentyl phosphinic acid, 10 g (0.0354 moles) of oleic acid and 0.25 mL (0.0012 moles) of di-tert-amylperoxide are mixed in a 50 mL single neck flask. The mixture is purged with argon to remove oxygen and is heated under argon for 6 hours at 140° C. Tert-amyl alcohol is removed by distillation and 13.5 g (83% yield) of 10-[hydroxy-(2,4,4-trimethyl-pentyl)-phosphinoyl]-octadecanoic acid is obtained as a viscous oil.

WORKUP

后处理

  1. customThe mixture is purged with argon
  2. customto remove oxygen
  3. customTert-amyl alcohol is removed by distillation