反应详情

A solution of 150 mg (0.317 mmol) acetic acid[2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazol-5-yl]-phenyl-methyl ester in 8 ml THF:MeOH=1:2 is hydrogenated in the presence of 50 mg Pd/C (Engelhard 4505). Then the catalyst is filtered off and the filtrate is concentrated in vacuo to afford 120 mg of the title compound as a colorless oil.

1. filtrationThen the catalyst is filtered off
2. concentrationthe filtrate is concentrated in vacuo