反应详情

The title compound was synthesized as described for example 11i in 90% yield starting from N-((5-bromo-2-fluorophenyl)(2-cyano-3-fluorophenyl)methylene)propane-2-sulfinamide (0.980 g, 2.38 mmol) and 4-bromo-2-(trifluoromethyl)pyridine (0.646 g, 2.86 mmol). Purification was achieved by flash chromatography using a gradient of 100% CH2Cl2 to 30% 0.1M NH3 in MeOH in CH2Cl2.

1. customPurification