HCID 58579486, compound → (5-(3-Amino-1-(3-bromophenyl)-4-fluoro-1H-isoindol-1-yl)-2-methoxy-3-methylphenyl)methanol

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Reaction Steps

The title compound was synthesized as described for Example 35i in 54% yield, starting from of (5-bromo-2-methoxy-3-methylbenzyloxy)(tert-butyl)dimethylsilane (1.44 g, 4.17 mmol) and (E)-N-((3-bromophenyl)(2-cyano-3-fluorophenyl)methylene)-2-methylpropane-2-sulfinamide (1.415 g, 3.47 mmol). MS (ES+) m/z 455, 457 [M+H]+.

Provenance & Evidence