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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1662424Generated: October 30, 2026

(2-(1,1-Dimethylethyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol → [2'-Fluoro-5'-methoxy-2-(1-methoxy-2,2-dimethyl-but-3-enyl)-biphenyl-4-yl]-methanol

https://huagongshe.com/reaction/1662424

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-(1,1-Dimethylethyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanolHCID 57705540—
Reactant2'-Fluoro-5'-methoxy-2-(1-methoxy-2,2-dimethyl-but-3-enyl)-biphenyl-4-carboxylic acid methyl esterHCID 57706181—
Product[2'-Fluoro-5'-methoxy-2-(1-methoxy-2,2-dimethyl-but-3-enyl)-biphenyl-4-yl]-methanolHCID 57467633—

Reaction Steps

Compound 66.41F was synthesized from 66.41E by a method analogous to that used to prepare compound 8.9 from 8.8. MS ESI m/e: 345.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030354B2
Source datasetuspto-grants-2011_10
ORD IDord-9f7e0b4de6fd434a80fe91513a23c9aa
Source noteuspto-grants-2011_10